When speaking to audiences, dealing with hecklers is always a concern. This is especially the case if you are delivering bad news or talking about something unpopular or contentious.
Two ways you can simply deal with hecklers are to one; acknowledge their point of view and right to speak and two; use humour to defuse the situation. And self deprecating humour is safer than making fun of the heckler himself.
Recently Barrack Obama was heckled during a speech to Israeli Youth – 2013. You can see how he handled it in this You Tube clip. Enjoy